Platelet-rich plasma: a review of biology and applications in plastic surgery.

نویسندگان

  • Barry L Eppley
  • William S Pietrzak
  • Matthew Blanton
چکیده

Healing of hard and soft tissue is mediated by a complex array of intracellular and extracellular events that are regulated by signaling proteins, a process that is, at present, incompletely understood. What is certain, however, is that platelets play a prominent if not deciding role. Controlled animal studies of soft and hard tissues have suggested that the application of autogenous platelet-rich plasma can enhance wound healing. The clinical use of platelet-rich plasma for a wide variety of applications has been reported; however, many reports are anecdotal and few include controls to definitively determine the role of platelet-rich plasma. The authors describe platelet biology and its role in wound healing; the preparation, characterization, and use of platelet-rich plasma; and those applications in plastic surgery for which it may be useful.

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عنوان ژورنال:
  • Plastic and reconstructive surgery

دوره 118 6  شماره 

صفحات  -

تاریخ انتشار 2006